1339Measles and Mumps Antibody Response in Young Adults after a Third Dose of Measles-Mumps-Rubella Vaccine
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چکیده
1339. Measles and Mumps Antibody Response in Young Adults after a Third Dose of Measles-Mumps-Rubella Vaccine Amy Parker Fiebelkorn, MSN, MPH; Laura Coleman, PhD, RD; Edward Belongia, MD; Sandra Freeman, CCRC; Daphne York, CCRP; Daoling Bi, MS; Cheryl Zhang, MD* (deceased); Laurie Ngo,; Steven Rubin, PhD; Ashwin Kulkarni,; Susette Audet, BS; Judith Beeler, MD; Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA; Marshfield Clinic Research Foundation, Marshfield, WI; Abbott Nutrition, Columbus, OH; Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD
منابع مشابه
Mumps Antibody Response in Young Adults After a Third Dose of Measles-Mumps-Rubella Vaccine
BACKGROUND Mumps outbreaks in populations with high 2-dose measles-mumps-rubella (MMR) vaccine coverage raise the question whether a third dose of MMR vaccine (MMR3) is needed. However, data on the immunogenicity of MMR3 are limited. We assessed mumps virus neutralizing antibody levels pre- and post-MMR3 in a nonoutbreak setting. METHODS Mumps antibody titers were assessed at baseline, 1 mont...
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BACKGROUND High attack rates among vaccinated young adults reported during the 2006 mumps outbreak in the United States heightened concerns regarding mumps vaccine failure. METHODS Serum specimens from university students and staff were tested for mumps immunoglobulin (Ig) G by enzyme immunoassay (EIA). A subset of participants vaccinated for < or =5 years and > or =15 years were tested by ne...
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Background Recent mumps outbreaks among 2-dose measles mumps rubella (MMR) vaccine recipients have raised questions regarding the potential benefits of a third dose of vaccine (MMR3). If MMR3 provides a sustained elevation in mumps antibody, it may be beneficial for certain at-risk groups or as an outbreak control measure. Methods Sera were collected immediately prior to MMR3 and at 1 month a...
متن کاملPersistence of measles, mumps, and rubella antibodies in an MMR-vaccinated cohort: a 20-year follow-up.
BACKGROUND The persistence of antibodies against measles, mumps, and rubella induced by the measles-mumps-rubella (MMR) vaccine and the kinetics of antibody decline after the second MMR vaccine dose were studied in the same cohort for 20 years. METHODS Measles, mumps, and rubella antibodies were measured by enzyme immunoassay in 20-year follow-up serum samples (n= 183) of twice-vaccinated ind...
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Although the measles-mumps-rubella (MMR) vaccine is not recommended for mumps postexposure prophylaxis (PEP), data on its effectiveness are limited. During the 2009-2010 mumps outbreak in the northeastern United States, we assessed effectiveness of PEP with a third dose of MMR vaccine among contacts in Orthodox Jewish households who were given a third dose within 5 days of mumps onset in the ho...
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